Manchester City manager Pep Guardiola believes the teams below them improve next season however the Spaniard has insisted his team will be stronger.

Oklahoma's Attorney General accused Johnson & Johnson of a "multi-billion-dollar brainwashing campaign" to get doctors to overprescribe opioids, downplaying the addiction risks. J&J shares surged after the ruling.

US opioid crisis: Pharmaceutical giants reach deal to avoid lawsuit

In Mexico, poppy farming and the production of opium paste – heroin's main ingredient – have long been the main source of revenue for many impoverished rural communities. But this is no longer the case, with both organised crime and addicts now turning to fentanyl – a cheap, ultraconcentrated and synthetic opioid – as their drug of choice. Our Mexico correspondents Laurence Cuvillier and Matthieu Comin report from Guerrero State, where a rural exodus is underway.

McKinsey & Company, the consultant to blue-chip corporations and governments around the world, has agreed to pay $573 million to settle investigations into its role in helping “turbocharge” opioid sales, a rare instance of it being held publicly accountable for its work with clients.

Four drugs companies in the United States have agreed to pay up to $26 billion to settle claims that they fuelled an opioid addiction crisis in the country. The deal was unveiled by a group of state attorneys general and could settle thousands of cases over the epidemic. Opioid addiction is estimated to have claimed over one million lives in the US. Individual states and local governments will now have to sign up to the deal, but there are divisions over how the payout will be shared.

Handing the win to pharmaceutical companies, the judge said the plaintiffs hadn't proven that deceptive marketing by the firms led to a rise in unnecessary opioid prescriptions.

Walmart, Walgreens and CVS have vowed to appeal after two counties in the state of Ohio successfully sued the pharmacy giants for their role in the opioid epidemic.

"Freedom Convoy" protests are still paralysing the Canadian capital Ottawa. The truckers are also blocking the busiest international crossing in North America. The Ambassador Bridge between Detroit, Michigan and Windsor, Ontario carries a fourth of all trade between Canada and the US. Canadian lawmakers are becoming increasingly worried about the economic effects of the protests against vaccine mandates and other Covid-19 restrictions. Our correspondents François Rihouay, Joanne Profeta and Gloria Henriquez report.

For a second day, police have moved in to disperse the so-called "freedom convoy" near the Parliament. Downtown Ottawa has been occupied by protesters and their trucks since late last month.

Smart algorithms can bundle and evaluate information at lightning speed, which helps determine what content is shown to users. This benefits apps like Shein and TikTok enormously.

President Lopez Obrador has written to Xi Jinping amid a spat with the US about the trafficking of fentanyl. The Mexican president has asked China for information on drug shipments.